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Protective effects of aspirin and vitamin C against corn syrup consumption-induced cardiac damage through sirtuin-1 and HIF-1 alpha pathway

Protective effects of aspirin and vitamin C against corn syrup consumption-induced cardiac damage through sirtuin-1 and HIF-1 alpha pathway

Topsakal, Senay; AŞCI, Halil; YEŞİLOT, Sukriye; Savran, Mehtap; Ozmen, Ozlem; CANKARA, Fatma Nihan; SAYGIN, Mustafa
URI: http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/77073

Description:

Objective: The aim of this study was to investigate the protective effects of aspirin (AS) and vitamin C (VC) against cardiac damage induced by chronic corn syrup (CS) consumption via a mechanism involving sirtuin-1 (ST-1), hypoxia-inducible factor-1 alpha (HIF-1 alpha), and the caspase-3 pathway in rats.

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