Ethnopharmacological relevance: This paper provides significant ethnobotanical information on medicinal plants in Espiye in the Black Sea Region. Recording such data calls for urgency. This is the first ethnobotanical study in which statistical calculations about plants are carried out by means of FIC method in Northern (Espiye-Giresun) part of Turkey. This study aims to identify the wild plants collected for medicinal purposes by locals of Espiye which is located in the Black Sea Region of Turkey, and to identify the uses and local names of these wild plants.