Objective: The objective of the study is to evaluate the fenestration and dehiscence types in Turkish human skulls according to 2 classifications. Methods: For the study, 297 skulls with 1808 teeth were analyzed from a collection of anatomy laboratories of 2 universities. Yang’s and Pan’s classifications were used to determine fenestration and dehiscence types. Chi-square and Fisher’s exact tests were used for statistical analysis. Results: There was no statistical difference in the presence of fenestration and dehiscence between the maxilla and mandible (P >.05). Type IV was most common fenestration in the maxilla (P =.029). Types III and IV were the most common types in the mandible (P <.05). CI DI and CI DII were the most common dehiscence in the maxilla and mandible, respectively (P <.05). The maxillary first premolar showed the highest prevalence of fenestration (P <.001). The mesial root of the maxillary first molar showed the highest prevalence of dehiscence (P <.05). Conclusion: The prevalence of fenestration and dehiscence was 8.70% and 10.06%, respectively, in Turkish human skulls. Fenestration in maxilla were mostly located in middle and apical of the root (type IV), the ones in mandible were in the coronal third of the root (type III). The most affected tooth was the maxillary first premolar for fenestration and the maxillary first molar for dehiscence. Most dehiscences in the maxilla were located in the coronal (CI DI), and they were located in both the coronal and middle thirds (CI DII) in the mandible.