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Sodium Management in Kidney Disease: Old Stories, New Tricks

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dc.creator Afsar, Baris
dc.creator Elsurer Afsar, Rengin
dc.creator Ikizler, Talat Alp
dc.date 2023-03-01T00:00:00Z
dc.date.accessioned 2025-02-25T10:22:37Z
dc.date.available 2025-02-25T10:22:37Z
dc.identifier 5af5ff1e-8f64-45d6-ae24-de84e0b16592
dc.identifier 10.1016/j.semnephrol.2023.151407
dc.identifier https://avesis.sdu.edu.tr/publication/details/5af5ff1e-8f64-45d6-ae24-de84e0b16592/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/99837
dc.description Excessive dietary sodium intake is associated with an increased risk of hypertension, especially in the setting of chronic kidney disease (CKD). Although implementation of a low-sodium diet in patients with CKD generally is recommended, data supporting the efficacy of this practice is mostly opinion-based. Few controlled studies have investigated the specific association of dietary sodium intake and cardiovascular events and mortality in CKD. Furthermore, in epidemiologic studies, the association of sodium intake with CKD progression, cardiovascular risk, and mortality is not homogeneous, and both low- and high-sodium intake has been associated with adverse health outcomes in different studies. In general, the adverse effects of high dietary sodium intake are more apparent in the setting of advanced CKD. However, there is no established definitive target level of dietary sodium intake in different CKD stages based on glomerular filtration rate and albuminuria/proteinuria. This review discusses the current challenges regarding the rationale of sodium restriction, target levels and assessment of sodium intake, and interventions for sodium restrictions in CKD in relation to clinical outcomes.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Sodium Management in Kidney Disease: Old Stories, New Tricks
dc.type info:eu-repo/semantics/article


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