| dc.creator |
Akdağ, Mevlüt |
|
| dc.creator |
Önkol, Tijen |
|
| dc.creator |
Arslan, Gülnur |
|
| dc.date |
2020-02-27T00:00:00Z |
|
| dc.date.accessioned |
2025-02-25T10:32:19Z |
|
| dc.date.available |
2025-02-25T10:32:19Z |
|
| dc.identifier |
76d48b1c-f0f3-4f18-ba0a-c427e8943ca4 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/76d48b1c-f0f3-4f18-ba0a-c427e8943ca4/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/100205 |
|
| dc.description |
<p>In the 21th century, many drug targets have been investigated intensely and therefore it is necessary to find new drug substances for new targets. 2-(3H)-Benzothiazolone derivatives have a potential for phamaceutical industry. The ring can be substitued on diverse positions and chemists can obtain different new derivatives. In the literature, it has been reported that various derivatives of the 3-substituted 2-(3H)-benzothiazolones have been obtained and these have high antimicrobial1, antiviral1, antinociceptive2, analgesic3, antiinflamatory3, and anticonvulsan4activities as well as high affinity to serotonin receptors5. Based on this information, we designed some amide derivatives bearing 5-chloro-2-(3H)-benzothiazolone ring and these were synthesized in three steps and finally the structure of the substances are verified analyzing NMR spectra and purity was controlled using LC-MS.Later, we will evaluate their biological activities. <br></p> |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Synthesis of 3-Substitued-5-Chloro-2-(3H)-Benzothiazolone Derivatives |
|
| dc.type |
info:eu-repo/semantics/conferenceObject |
|