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Probiotics, Live Biotherapeutic Products (LBPs), and Gut-Brain Axis Related Psychological Conditions: Implications for Research and Dietetics

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dc.creator AĞAGÜNDÜZ, DUYGU
dc.creator Bingöl, Feray Gençer
dc.creator Özenir, Çiler
dc.creator ÖZOĞUL, FATİH
dc.creator Çelik, Elif
dc.creator Capasso, Raffaele
dc.creator Cemali, Özge
dc.date 2023-08-01T00:00:00Z
dc.date.accessioned 2025-02-25T10:35:00Z
dc.date.available 2025-02-25T10:35:00Z
dc.identifier 9c53cd15-6761-4a88-adbd-738401632636
dc.identifier 10.1007/s12602-023-10092-4
dc.identifier https://avesis.sdu.edu.tr/publication/details/9c53cd15-6761-4a88-adbd-738401632636/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/100717
dc.description It is well-known that probiotics have key roles in the crosstalk between the gut and brain in terms of nutrition and health. However, when investigating their role in nutrition and health, it can be important to discriminate probiotics used as foods, food supplements, or drugs. For clarification of this terminology, the Food and Drug Administration (FDA) has established a new “live biotherapeutic products” (LBP) category, expressing pharmaceutical expectations and to reduce confusion in the literature. Growing evidence advises that the community of microorganisms found in the gut microbiota is associated with psychological conditions. Hence, it is thought that LBPs may positively affect depression, anxiety, bipolar disorder, and schizophrenia by reducing inflammation, improving gut microbiota, and balancing gut neurometabolites. This review focuses on the specific position of probiotics as LBPs in psychological conditions. Condition-specific potential pathways and mechanisms of LBPs and the prominent strains are discussed in the light of novel studies for future research, dietetic and pharmaceutical applications.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Probiotics, Live Biotherapeutic Products (LBPs), and Gut-Brain Axis Related Psychological Conditions: Implications for Research and Dietetics
dc.type info:eu-repo/semantics/article


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