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Biosynthesis of ZnO nanoparticles using Laurus nobilis leaf extract and investigation of antiproliferative and antibacterial activity potential

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dc.creator Çırrık, Cennet
dc.creator Ezer, Aleyna
dc.creator Akkoç, Senem
dc.creator Mert Sivri, firdevs
dc.creator önem, ebru
dc.date 2023-08-27T00:00:00Z
dc.date.accessioned 2025-02-25T10:35:16Z
dc.date.available 2025-02-25T10:35:16Z
dc.identifier a08c0ec3-a19c-4845-976c-4e1799bc70b9
dc.identifier 10.21448/ijsm.1266244
dc.identifier https://avesis.sdu.edu.tr/publication/details/a08c0ec3-a19c-4845-976c-4e1799bc70b9/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/100774
dc.description Nanotechnology has recently emerged as an essential field of study in modern materials science. The green synthesis of nanoparticles using plant extracts is of great interest because it is cost-effective, eco-friendly, and suitable for large-scale production. The study highlights the synthesis of ZnO nanoparticles (ZnO NPs) using Laurus nobilis (L. nobilis) leaf extract and their characterization and biological activities for potential applications in the biomedical field. ZnO NPs were synthesized using Laurus nobilis leaf extract. The synthesized ZnO NPs were characterized by UV-Vis spectroscopy, TEM, XRD, and FT-IR. According to TEM and XRD diffraction analysis, with a mean particle size of 16 ± 5 nm, it was found that the synthesized ZnO NPs contain a hexagonal wurtzite structure. ZnO NPs have antibacterial activity against Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli). The antiproliferative activity of ZnO NPs was tested against the human colon cancer cell line and mouse normal fibroblast cell line using MTT assay in vitro. The results show that the prepared nanoparticles had antiproliferative in screened incubation time and concentrations.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Biosynthesis of ZnO nanoparticles using Laurus nobilis leaf extract and investigation of antiproliferative and antibacterial activity potential
dc.type info:eu-repo/semantics/article


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