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Comparative safety review of antithrombotic treatment options for patients with atrial fibrillation undergoing percutaneous coronary intervention

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dc.creator Gupta, Rahul
dc.creator Sood, Aayushi
dc.creator Lee, Duo
dc.creator Ulusan, Sebahat
dc.creator Susarla, Shriraj
dc.creator Pyrpyris, Nikolaos
dc.creator Erbay, Muhammed Ibrahim
dc.creator Wilson, Tasha Phillips
dc.creator Mares, Adriana C.
dc.date 2024-01-01T00:00:00Z
dc.date.accessioned 2025-02-25T10:36:38Z
dc.date.available 2025-02-25T10:36:38Z
dc.identifier b297dbe3-6505-4e7a-982f-e612eafbaf70
dc.identifier 10.1080/14740338.2024.2305367
dc.identifier https://avesis.sdu.edu.tr/publication/details/b297dbe3-6505-4e7a-982f-e612eafbaf70/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/101020
dc.description Introduction: Balancing antithrombotic therapy for atrial fibrillation (AF) patients undergoing percutaneous coronary intervention (PCI) remains a clinical challenge due to coexisting thrombogenic risks. This review emphasizes the delicate balance required to prevent ischemic events while minimizing bleeding complications, particularly in the context of risk assessment. Areas covered: This review spans from 2010 to October 2023, exploring the complexities of antithrombotic management for AF patients undergoing PCI. It stresses the need for personalized treatment decisions to optimize antithrombotic therapies effectively. Expert opinion: The evolving evidence supports double antithrombotic therapy (DAT) over triple antithrombotic therapy (TAT) for these patients, showcasing a more favorable safety profile without compromising efficacy. Non-vitamin K antagonist oral anticoagulant (NOAC)-based DAT strategies exhibit superiority in reducing major bleeding events while effectively preventing ischemic events. Recommendations from the 2023 European Society of Cardiology (ESC) Guidelines advocate for NOAC-based DAT post-PCI, endorsing safer antithrombotic profiles. Challenges persist for specific patient categories requiring both oral anticoagulants and antiplatelets, necessitating personalized approaches. Future advances in intravascular imaging and novel coronary stent technologies offer promising avenues to optimize outcomes and influence antithrombotic strategies in AF-PCI patients.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Comparative safety review of antithrombotic treatment options for patients with atrial fibrillation undergoing percutaneous coronary intervention
dc.type info:eu-repo/semantics/article


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