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Successful management of imatinib despite alopecia and nail necrosis

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dc.creator Ergene, Ulku
dc.creator Ozbalci, Demircan
dc.date 2013-04-01T00:00:00Z
dc.date.accessioned 2025-02-25T10:37:41Z
dc.date.available 2025-02-25T10:37:41Z
dc.identifier c1a049b6-4392-4dd6-a7ad-b6aac8ec4b40
dc.identifier 10.1016/j.transci.2013.01.002
dc.identifier https://avesis.sdu.edu.tr/publication/details/c1a049b6-4392-4dd6-a7ad-b6aac8ec4b40/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/101230
dc.description Imatinib mesylate selectively inhibits bcr/abl and other non-specific tyrosine kinases, such as c-kit and platelet derived growth factor (PDGF) receptor and successfully used to treat chronic myeloid leukaemia (CML). In most cases, the drug is well tolerated: however, side effects can be seen. Hair loss and paronychia inflammation were often reported with Imatinib, but total alopecia was rarely mentioned. We report a CML patient who was presented with alopecia and paronychia inflammation probably induced by imatinib therapy. We have successfully treated our patient by cessation and then re-applying therapy with lower doses after improvement of lesions and have not found a similar report in literature. © 2013 Elsevier Ltd.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Successful management of imatinib despite alopecia and nail necrosis
dc.type info:eu-repo/semantics/article


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