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The global, regional, and national burden of urolithiasis in 204 countries and territories, 2000–2021: a systematic analysis for the Global Burden of Disease Study 2021

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dc.creator Mahmoud, Mansour Adam
dc.creator Lim, Stephen S.
dc.creator Lee, Shaun Wen Huey
dc.creator Lee, Sang-Woong
dc.creator Kim, Min Seo
dc.creator Jazayeri, Seyed Behzad
dc.creator Jayarajah, Umesh
dc.creator Ilic, Milena D.
dc.creator Ilic, Irena M.
dc.creator Hay, Simon I.
dc.creator Ghamari, Seyyed-Hadi
dc.creator Getachew, Motuma Erena
dc.creator Gebremeskel, Teferi Gebru
dc.creator Fatehizadeh, Ali
dc.creator Esezobor, Christopher Imokhuede
dc.creator Elmonem, Mohamed A.
dc.creator Elhadi, Muhammed
dc.creator Digesa, Lankamo Ena
dc.creator Dadras, Omid
dc.creator Cruz-Martins, Natalia
dc.creator Charan, Jaykaran
dc.creator Caetano dos Santos, Florentino Luciano
dc.creator Bikbov, Boris
dc.creator Bhaskar, Sonu
dc.creator Bhardwaj, Pankaj
dc.creator Bhardwaj, Nikha
dc.creator Ayana, Tegegn Mulatu
dc.creator Aravkin, Aleksandr Y.
dc.creator Arabloo, Jalal
dc.creator Alvand, Saba
dc.creator Almidani, Omar
dc.creator Al-Aly, Ziyad
dc.creator Abbasi-Kangevari, Mohsen
dc.creator Schneider, Rachel D.
dc.creator Dodge, Maxwell
dc.creator Berice, Bétyna N.
dc.creator Han, Hannah
dc.creator Awedew, Atalel Fentahun
dc.creator Dai, Xiaochen
dc.creator Dirac, M. Ashworth
dc.creator Misganaw, Awoke
dc.creator Zumla, Alimuddin
dc.creator Zhang, Zhi-Jiang
dc.creator Zastrozhin, Michael
dc.creator Zahir, Mazyar
dc.creator Yiğit, Arzu
dc.creator Yazdanpanah, Fereshteh
dc.creator Yahyazadeh Jabbari, Seyed Hossein
dc.creator Wolde, Asrat Arja
dc.creator Vo, Bay
dc.creator Valizadeh, Rohollah
dc.creator Valadan Tahbaz, Sahel
dc.creator Tolani, Musliu Adetola
dc.creator Tan, Ker-Kan
dc.creator YİĞİT, Vahit
dc.creator Skryabina, Anna Aleksandrovna
dc.creator Skryabin, Valentin Yurievich
dc.creator Singh, Jasvinder A.
dc.creator Schumacher, Austin E.
dc.creator Remuzzi, Giuseppe
dc.creator Rawassizadeh, Reza
dc.creator Rashidi, Mohammad-Mahdi
dc.creator Perico, Norberto
dc.creator Pawar, Shrikant
dc.creator Ortiz, Alberto
dc.creator Murray, Christopher J.L.
dc.creator Moradi, Maryam
dc.creator Moni, Mohammad Ali
dc.creator Mokdad, Ali H.
dc.creator Mirrakhimov, Erkin M.
dc.creator Mihrtie, Gedefaye Nibret
dc.creator Michalek, Irmina Maria
dc.creator Mestrovic, Tomislav
dc.creator Mentis, Alexios-Fotios A.
dc.creator Malik, Ahmad Azam
dc.date 2024-12-01T00:00:00Z
dc.date.accessioned 2025-02-25T10:41:06Z
dc.date.available 2025-02-25T10:41:06Z
dc.identifier ed08bb90-7320-435a-939b-790e9fa986a9
dc.identifier 10.1016/j.eclinm.2024.102924
dc.identifier https://avesis.sdu.edu.tr/publication/details/ed08bb90-7320-435a-939b-790e9fa986a9/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/101840
dc.description Background: Urolithiasis is a common urological problem that is associated with high morbidity. A comprehensive assessment of the non-fatal and fatal health trends of urolithiasis by age, sex, and geography over time is necessary to inform policy to control this surgically managed non-communicable disease. Methods: This study was conducted using the standard GBD methodology and analytic tools. Cause-specific mortality rate (CSMR) was estimated using vital registration and verbal autopsy data and the Cause of Death Ensemble model (CODEm) modelling tool. CSMR estimates and incidence data from medical insurance claims and hospital discharges were analysed using a Bayesian meta-regression modelling tool, DisMod-MR 2.1, to estimate age-, sex-, and location-specific incidence of urolithiasis between 2000 and 2021. Disability-adjusted life-years (DALYs) were the sum of years of life lost (YLL) and years lived with disability (YLDs). YLLs due to urolithiasis were calculated by multiplying the estimated number of deaths by the standard life expectancy at the age of death. YLDs were estimated by multiplying the disability weight by the symptomatic proportion of urolithiasis cases. The Global Burden of Diseases study used de-identified data, approved by the University of Washington IRB (Study Number 9060). Findings: There were 106 million (95% UI 88.3–129.0) incident cases of urolithiasis in 2021, of which 67% were in men (71.1 million [59.4–86.2)]). The global number of incident cases, deaths, and DALYs increased by 26.7% (23.8–29.8), 60.3% (41.5–84.7), and 34.5% (24.6–47.3), respectively, between 2000 and 2021. The global age-standardised incidence rate of urolithiasis experienced a significant decrease of 17.5% (14.7–20.0), while the age-standardised DALYs rate saw a reduction of 15.1% (6.8–21.3). Twelve GBD regions showed declining trends in the age-standardised incidence rate of urolithiasis between 2000 and 2021, and the remaining nine GBD regions had an increasing trend of age-standardised rates of urolithiasis. A significant increase in the age-standardised incidence rate of urolithiasis was observed in Central America, Tropical Latin America, and the Caribbean regions, whereas notable decline was observed in east Asia, eastern Europe, central Europe, and high-income North America. It was observed that the global age-standardised death rate was less than 0.5 per 100,000 across all GBD regions and less than 1 per 100,000 across all SDI quintiles, with fairly stable global age-standardised death rates of urolithiasis between 2000 and 2021. The age-standardised incidence rate of urolithiasis was 837 (688–1034) in low SDI regions and 1443 (12,108–1734) in high-middle SDI regions. Furthermore, the age-standardised DALY rate showed a decreasing trend across all SDI quintiles over the same period: high-middle SDI (−28.9% [–34.4 to −23.0]), middle SDI (−22.6% [–30.5 to −10.9]), and low-middle SDI (−2.9% [–15.8 to 12.9]). Interpretation: Global urolithiasis incidence and DALY rates have decreased, while the death rate has stabilised worldwide, showing significant variability among regions, SDI levels, and countries. This could be due to effective preventive measures c on urolithiasis risk factors, effective public health education, lifestyle changes, and early interventions and improved health care access at the global level. This analysis offers relevant insights into global, regional, and country-specific urolithiasis trends. Funding:Bill & Melinda Gates Foundation.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title The global, regional, and national burden of urolithiasis in 204 countries and territories, 2000–2021: a systematic analysis for the Global Burden of Disease Study 2021
dc.type info:eu-repo/semantics/article


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