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Machine learning-based analysis of MRI radiomics in the discrimination of classical and non-classical polycystic over syndrome

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dc.creator RONA, GUNAY
dc.creator EVRİMLER, ŞEHNAZ
dc.creator Özçelik, Serhat
dc.creator Arifoglu, Meral
dc.creator Duzkalir, Hanife Gulden
dc.creator Zengin Fıstıkçıoğlu, Neriman
dc.creator AYDİN, KADRİYE
dc.creator Tekin, Ahmet
dc.date 2024-03-31T00:00:00Z
dc.date.accessioned 2025-02-25T10:41:29Z
dc.date.available 2025-02-25T10:41:29Z
dc.identifier f2f4beaa-1722-427f-9e08-28087f29c781
dc.identifier 10.17826/cumj.1393084
dc.identifier https://avesis.sdu.edu.tr/publication/details/f2f4beaa-1722-427f-9e08-28087f29c781/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/101912
dc.description Purpose: The aim of this study is to investigate the value of radiomics analysis on T2-weighted Magnetic Resonance imaging (MRI) images in differentiating classical and non-classical polycystic ovary syndrome (PCOS). Materials and Methods: A total of 202 ovaries from 101 PCOS patients (mean age of 23±4 years) who underwent pelvic MRI between 2014 and 2022, were included in the study. Of the patients, 53 (52.5%) were phenotype A, 12 (11.9%) were phenotype B, 25 were phenotype C (25.1%), and 11 were phenotype D (10.9%). 130 (64.4%) of the ovaries were classical PCOS, 72 (35.6%) were non-classical PCOS. The ovaries were manually segmented in all axial sections using the 3D Slicer program. A total of 851 features were extracted. Python 2.3, Pycaret library was used for machine learning (ML) analysis. Datasets were randomly divided into train (70 %, 141) and test (30 %, 61) datasets. The performances of ML algorithms were compared with AUC, accuracy, recall, precision and F1 scores. Results: Accuracy and AUC values in the training set ranged from 57%-73% and 0.50-0.73, respectively. The two best ML algorithms were Random Forest (rf) (AUC:0.73, accuracy:73%) and Gradient Boosting Classifier (gbc) (AUC:0.71, accuracy:70%). AUC, accuracy, recall and precision values and F1 score of the blend model obtained from these two models were 0.70, 73 %, 56 %, 66%, 58%, respectively. Conclusion: Radiomic features obtained from T2W MRI are successful in distinguishing between classical and non-classical PCOS.
dc.language eng
dc.rights info:eu-repo/semantics/openAccess
dc.title Machine learning-based analysis of MRI radiomics in the discrimination of classical and non-classical polycystic over syndrome
dc.type info:eu-repo/semantics/article


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