| dc.creator |
CELIK, Sefa |
|
| dc.creator |
KECEL GUNDUZ, Serda |
|
| dc.date |
2017-05-11T00:00:00Z |
|
| dc.date.accessioned |
2019-07-09T12:00:15Z |
|
| dc.date.available |
2019-07-09T12:00:15Z |
|
| dc.identifier |
http://dergipark.org.tr/sdufenbed/issue/34634/382551 |
|
| dc.identifier |
10.19113/sdufbed.12478 |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/46663 |
|
| dc.description |
In this study, eight possible stable conformers of the Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) dipeptides, which show the most significant inhibition in cervical carcinoma cells opposite to HT-29 and MCF-7 cells, performed depending on the obtained conformational analysis. The possible stable geometries were determined with the aid of φ, Ψ backbone and c chain dihedral angles. Available all conformers and their energies were calculated and made comparison with the quantum chemical ab-initio results. The Van der Waals, electrostatic , torsional , interaction energies between side and main chains of aminoacids and total energies of cysteine containing dipeptides were computed by using Fortran program. |
|
| dc.format |
application/pdf |
|
| dc.publisher |
Süleyman Demirel University |
|
| dc.publisher |
Süleyman Demirel Üniversitesi |
|
| dc.relation |
http://dergipark.org.tr/download/article-file/409366 |
|
| dc.source |
Volume: 21, Issue: 2
306-310 |
en-US |
| dc.source |
1308-6529 |
|
| dc.subject |
Cyclic dipeptides,Conformational analysis; DFT |
|
| dc.title |
Conformational Analysis of Cyclo(Tyr-Cys) and Cyclo(Phe-Cys) Dipeptides |
en-US |
| dc.type |
info:eu-repo/semantics/article |
|