| dc.creator |
Kıdır, Mehtap |
|
| dc.date |
2014-01-09T14:53:01Z |
|
| dc.date.accessioned |
2019-07-09T12:09:04Z |
|
| dc.date.available |
2019-07-09T12:09:04Z |
|
| dc.identifier |
http://dergipark.org.tr/sdutfd/issue/21015/225985 |
|
| dc.identifier |
10.17343/sdutfd.06814 |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/47668 |
|
| dc.description |
The relation of vitamin D with immune system, skin and cancer.In humans, approximately 95% of the total requirement for vitamin D is synthesized in the skin by the effectsof sunlight. The active vitamin D synthesis from 25 (OH) D takes place via the 1-alpha hydroxylase enzymeboth in renal and non-renal tissues. The effect of vitamin D on the receptor level is through active vitaminD. Vitamin D receptors are shown in more than 30 tissues. Non-classical effects of vitamin D are groupedunder three main headings: Regulation of hormone secretion, regulation of immune function, regulation ofcell proliferation and differentiation. The relationship immune system, skin diseases cancer and vitamin Dis the most widely researched topics |
|
| dc.description |
İnsanlarda D vitamini ihtiyacının yaklaşık % 95'i güneş ışınlarının etkisiyle deride sentezlenmektedir. Böbrek dışı dokularda da 1-alfa hidroksilaz enzimi aracılığıyla aktif vitamin D sentezi gerçekleşmektedir. D vitamininin reseptör düzeyindeki etkisi aktif vitamin D sayesinde olur. Otuzdan fazla dokuda vitamin D reseptörleri gösterilmiştir. Vitamin D'nin iskelet sistemi dışındaki etkileri 3 ana başlık altında toplanmaktadır: Hormon sekresyonunun regülasyonu, immün fonksiyonların regülasyonu, hücre proliferasyon ve farklılaşmasının düzenlenmesi. İmmun sistem, cilt hastalıkları, kanser vitamin D ile ilişkisi en çok araştırılan konular arasındadır.Anahtar Kelimeler: D vitamini; kemik dışı etkiler; immün sistem; deri; kanserSUMMARYIn humans, approximately 95% of the total requirement for vitamin D is synthesized in the skin by the effects of sunlight. The active vitamin D synthesis from 25 (OH) D takes place via the 1-alpha hydroxylase enzyme both in renal and non-renal tissues. The effect of vitamin D on the receptor level is through active vitamin D. Vitamin D receptors are shown in more than 30 tissues. Non-classical effects of vitamin D are grouped under three main headings: Regulation of hormone secretion, regulation of immune function, regulation of cell proliferation and differentiation. The relationship immune system, skin diseases and cancer between vitamin D is the most widely researched topics.Key words: Vitamin D; nonskeletal effects; immune system; skin; cancer |
|
| dc.format |
application/pdf |
|
| dc.language |
en |
|
| dc.publisher |
Süleyman Demirel University |
|
| dc.publisher |
Süleyman Demirel Üniversitesi |
|
| dc.relation |
http://dergipark.org.tr/download/article-file/196947 |
|
| dc.relation |
http://dergipark.org.tr/download/article-file/250353 |
|
| dc.relation |
http://dergipark.org.tr/download/article-file/250354 |
|
| dc.source |
Volume: 20, Issue: 4
158-161 |
en-US |
| dc.source |
1300-7416 |
|
| dc.source |
2602-2109 |
|
| dc.subject |
Vitamin D; immune system; skin; cancer |
|
| dc.subject |
D vitamini; immün sistem; deri; kanser |
|
| dc.title |
D VİTAMİNİNİN İMMÜN SİSTEM, DERİ VE KANSER İLE İLİŞKİSİ |
en-US |
| dc.type |
info:eu-repo/semantics/article |
|