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EFFECTS OF MANNITOL ON LIPID PEROXIDATION AND Na+-K+/ATPase ENZYME ACTIVITY IN EXPERIMENTAL HEAD TRAUMA

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dc.creator Aköz, Mehmet
dc.date 2010-10-28T11:53:36Z
dc.date.accessioned 2019-07-09T12:09:23Z
dc.date.available 2019-07-09T12:09:23Z
dc.identifier http://dergipark.org.tr/sdutfd/issue/21001/225781
dc.identifier 10.17343/sdutfd.45115
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/47823
dc.description ABSTRACT This study was designed to determine the effects of mannitol on tissue Na+/K+-ATP ase enzyme activity and malondialdehyde (MDA) levels in rabbit brain after experimental head trauma. Thirty New Zealand rabbits were divided equally into three groups: Group S(sham-operated group), group C(untreated group) and group M (mannitol treated group). Grup C and group M received head trauma with the weight drop method. Mannitol was administered 1.0 g/ kg i.v. immediately after the head trauma to group M. Head trauma was applied to the right side. One hour after trauma, brain cortices were resected from both sides and the Na+/K+-ATP ase enzyme activity and MDA levels were determined. The results were compared between S, M and C groups (p>0.05). Rectal temparature after the administration of mannitol in group M was found to be lower than groups S and C (p
dc.format application/pdf
dc.language en
dc.publisher Süleyman Demirel University
dc.publisher Süleyman Demirel Üniversitesi
dc.relation http://dergipark.org.tr/download/article-file/196826
dc.source Volume: 17, Issue: 3 7-12 en-US
dc.source 1300-7416
dc.source 2602-2109
dc.subject Mannitol, Kafa travmasi, Na+/K+-ATPaz, Malondialdehyde
dc.title EFFECTS OF MANNITOL ON LIPID PEROXIDATION AND Na+-K+/ATPase ENZYME ACTIVITY IN EXPERIMENTAL HEAD TRAUMA en-US
dc.type info:eu-repo/semantics/article


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