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Can Neutrophil Lymphocyte Ratio Predict the Thrombus Localization in Patient with Acute Pulmonary Embolism?

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dc.creator Bedel, Cihan; Health Science University Antalya Training and Research Hospital, Department of Emergency Medicine
dc.creator Korkut, Mustafa; Health Science University Antalya Training and Research Hospital, Department of Emergency Medicine
dc.date 2019-06-16T00:00:00Z
dc.date.accessioned 2019-07-09T12:12:21Z
dc.date.available 2019-07-09T12:12:21Z
dc.identifier http://dergipark.org.tr/sdusbed/issue/45828/513295
dc.identifier 10.22312/sdusbed.513295
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/48245
dc.description Amaç:Acil serviste sıklıkla görülen akut pulmoner emboli (PE) hayatı tehdit edicibir hastalıktır. Bu çalışmanın amacı, nötrofil lenfosit oranı (NLR) dahil olmaküzere trombüs lokalizasyonunun beyaz kan hücresi (WBC) alt tipleri ileilişkilerini belirlemektir.Materyal-Metot: 1Ocak 2017 - 30 Haziran 2018 tarihleri ​​arasında başvuran akut PE tanısı alanhastaların verilerini retrospektif olarak inceledik. Eşlik eden hastalıklar,risk faktörleri, klinik, laboratuvar ve radyolojik bulgular değerlendirildi.Bulgular:Hastaların yaş ortalaması 63,40 ± 17,11 idi  ve hastların 119'u (% 53,1) kadındı. En sıkgörülen şikayet dispne (% 62,5), en sık eşlik eden hastalık kronik obstrüktifakciğer hastalığı (% 30,4) ve immobilizasyon (% 21,4) en sık görülen riskfaktörü idi. Trombüs çoğunlukla bilateral pulmoner arterde (PA) (% 45,9) idi.Hastaların % 46,4'ünde trombüs, lober PA'da lokalize edildi. Ana PA'da trombüsolan hastalarda ortalama WBC, nötrofil, trombosit dağılım genişliği ve NLR,daha distal PA dallarında trombüs olanlara göre daha yüksekti. Hassasiyeti veözgüllüğü en yüksek olan parametre NLR olarak bulundu.Sonuç:Yüksek NLR, PE'li hastalarda proksimal lokalize trombüs ile bağımsız olarakilişkilidir.
dc.description Objective: Acutepulmonary embolism (PE), often seen in the emergency department, is a lifethreatening disease. The aim of this study was to determine the associations ofthrombus localization with white bloodcell (WBC) subtypes, including the neutrophil lymphocyte ratio (NLR).Material-Method:Weretrospectively analysed the data of patients who were diagnosed with acutePE  admitted from 1 January 2017 to 30June 2018. The accompanying disorders, risk factors, clinical, laboratory andradiological findings were retrospectively evaluated.Results: Themean age of the patients was 63.40±17.11years and 119 (53.1%) patients were female. The most frequent complaint wasdyspnea (62.5%), most frequent coexisting disease was chronic obstructivepulmonary disease (30.4%), immobilization (21.4%) was the most frequently seenrisk factor. Thrombus was mostly in bilateral pulmonary artery (PA) (45.9%). In46.4% of the patients, the thrombus was localized to the lobar PA. The meanWBC, neutrophil,  plateletdistribution width  and  NLRin the patients with thrombus in the main PA were higher than those in thepatients with thrombus in more distal PA branches. The parameter with the highest sensitivity and specificity was foundas NLR.Conclusions:High NLR  is independently associatedwith proximally localized thrombus in patients with PE.
dc.format application/pdf
dc.language en
dc.publisher Süleyman Demirel University
dc.publisher Süleyman Demirel Üniversitesi
dc.relation http://dergipark.org.tr/download/article-file/737193
dc.source Volume: 10, Issue: 2 115-119 en-US
dc.source 2146-1937
dc.source 2146-247X
dc.subject Pulmoner emboli,nötrofil lenfosit oranı
dc.subject Pulmonary embolism,neutrophil lymphocyte ratio
dc.title Can Neutrophil Lymphocyte Ratio Predict the Thrombus Localization in Patient with Acute Pulmonary Embolism? en-US
dc.title Can Neutrophil Lymphocyte Ratio Predict the Thrombus Localization in Patient with Acute Pulmonary Embolism? en-US
dc.type info:eu-repo/semantics/article


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