| dc.creator |
Savran, Mehtap; FACULTY OF MEDICINE |
|
| dc.creator |
Aşcı, Halil; FACULTY OF MEDICINE |
|
| dc.creator |
Şengeze, Nihat; FACULTY OF MEDICINE |
|
| dc.creator |
Önal, Özgür; FACULTY OF MEDICINE |
|
| dc.creator |
Demirci, Serpil; FACULTY OF MEDICINE |
|
| dc.date |
2019-12-13T00:00:00Z |
|
| dc.date.accessioned |
2020-01-02T08:30:57Z |
|
| dc.date.available |
2020-01-02T08:30:57Z |
|
| dc.identifier |
https://dergipark.org.tr/tr/pub/sdusbed/issue/50592/599102 |
|
| dc.identifier |
10.22312/sdusbed.599102 |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/49271 |
|
| dc.description |
Objective: Advancedage, as a cause of increased prevalence of co-morbidities, is one of the mainrisk factors for Alzheimer disease. Co-morbidities accompanying the Alzheimer as well as the disease itselfelicit polypharmacy which means two or more drugs used concomitantly. One ofthe undesirable results of polypharmacy is potential drug-drug interactions(pDDI). The study aimed to evaluate the pDDIsin Alzheimer patients.Material-Method: Filesof patient who applied to a XXX Outpatient Clinic of a tertiary hospital in XXXbetween 2016-2018 were evaluated retrospectively. Rate of polypharmacy,presence and type of pDDI were determinated.Results: In theanalyses of 115 files, mean age was 75.13+9.38 and frequency of polypharmacywas calculated as 53.9%. Presence of 3 or more co-morbidites was associatedwith polypharmacy. pDDI was detected in 77.4% of patients and type Cinteraction was the most common type. Quetiapine, citalopram/escitalopram,donepezil, risperidone and acetylsalicylic acid were the five drugs thatinteracted with the maximum number of other medications. Conclusion: The rate of polypharmacy and pDDI as aconsequence of polypharmacy could be higher in Alzheimer patients. Some pDDIscould impair the therapeutic effects of Alzheimer drugs in addition toundesirable effects. So the pDDI should be kept in mind when a new drug shouldbe added to Alzheimer patient. |
|
| dc.format |
application/pdf |
|
| dc.language |
en |
|
| dc.publisher |
Süleyman Demirel University |
|
| dc.publisher |
Süleyman Demirel Üniversitesi |
|
| dc.relation |
https://dergipark.org.tr/tr/download/article-file/882744 |
|
| dc.source |
Volume: 10, Issue: 4
381-388 |
en-US |
| dc.source |
2146-1937 |
|
| dc.source |
2146-247X |
|
| dc.subject |
Alzheimers disease,potential drug-drug interaction,elderly,polypharmacy |
|
| dc.title |
The Potential Drug-Drug Interactions in Alzheimer Patients’ Treatment |
tr-TR |
| dc.type |
info:eu-repo/semantics/article |
|