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A review of the role of platelet rich fibrin in healing and regenerative process and its use in orthopaedic surgery

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dc.creator Dülgeroğlu, Turan Cihan; KÜTAHYA SAĞLIK BİLİMLERİ ÜNİVERSİTESİ
dc.creator Şen, Baran; İZMİR ÇEŞME DEVLET HASTANESİ
dc.date 2019-09-01T00:00:00Z
dc.date.accessioned 2020-01-02T08:32:40Z
dc.date.available 2020-01-02T08:32:40Z
dc.identifier https://dergipark.org.tr/tr/pub/sdutfd/issue/48483/451366
dc.identifier 10.17343/sdutfd.451366
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/49318
dc.description Platelet-rich fibrin (PRF) is a naturally derived fibrinscaffold and second-generation platelet concentrate with great potential forpromoting wound healing and the regenerative process via the secretion ofdifferent cytokines and growth factors, enhanced osteoblast adhesion, andaugmentation of collagen protein expression. Given the significance of thescope of PRF in the field of orthopedic surgery, this study presents an overviewfor the role of PRF in the recovery and the regenerative process with emphasison its rationale for use and outcome in orthopedic surgery. In conclusion, PRFoffers a new dimension for clinical research with expanded range of potentialapplications in orthopedic surgery with a simpler preparation protocol, astronger and more stable fibrin polymerization leading to a physiologicarchitecture, occurrence of natural clot formation allowing formation of aflexible and fine fibrin network and a continual and steady release ofcytokines and growth factors, mimicking the requirements of the reparativetissue and wound healing processes. 
dc.format application/pdf
dc.language en
dc.publisher Süleyman Demirel University
dc.publisher Süleyman Demirel Üniversitesi
dc.relation https://dergipark.org.tr/tr/download/article-file/798707
dc.source Volume: 26, Issue: 3 354-361 en-US
dc.source 1300-7416
dc.source 2602-2109
dc.subject Platelet rich fibrin; wound healing; tissue regeneration; growth factors; orthopedic surgery
dc.title A review of the role of platelet rich fibrin in healing and regenerative process and its use in orthopaedic surgery en-US
dc.title Plateletten zengin fibrinin iyileşme ve rejenerasyon sürecindeki rolü ve ortopedik cerrahide kullanımına dair bir derleme tr-TR
dc.type info:eu-repo/semantics/article


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