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Synthesis, potentiometric titrations and antioxidant activities of some 4-acylamino-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives

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dc.creator Islamoglu, Fatih
dc.creator Bahceci, Sule
dc.creator Elmastas, Mahfuz
dc.creator Calapoglu, Mustafa
dc.creator Ozdemir, Mustafa
dc.creator Alkan, Muzaffer
dc.creator Yuksek, Haydar
dc.date 2008-08-31T21:00:00Z
dc.date.accessioned 2020-10-06T09:15:56Z
dc.date.available 2020-10-06T09:15:56Z
dc.identifier 01ab6c58-9034-4cec-81f4-07f99e19c08c
dc.identifier https://avesis.sdu.edu.tr/publication/details/01ab6c58-9034-4cec-81f4-07f99e19c08c/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/52008
dc.description Five novel 3-alkyl-4-cinnamoylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) were synthesized by the reactions of 3-alkyl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (I)with cinnamoyl chloride and characterized by elemental analyses and IR,(1)H NMR, (13)C NMR and UV spectral data. The newly synthesized compounds 2 were titrated potentiometrically with tetrabutylammonium hydroxide in four non-aqueous solvents such as isopropyl alcohol, t-butyl alcohol, acetonitrile and N,N-dimethylformamide and the half-neutralization potential values and the corresponding pK(a) values were determined for all cases. In addition, these new compounds (except compound 2a) and five recently reported 3-alkyl-4-isobutyrylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones (3) were screened for their antioxidant activities.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Synthesis, potentiometric titrations and antioxidant activities of some 4-acylamino-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives
dc.type info:eu-repo/semantics/article


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