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Evaluating The Antidepressant Efficacy of Aripiprazole Using a Chronic Mild Stress Model: An Experimental Study

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dc.creator EREN, Ibrahim
dc.creator DEMİRDAŞ, Arif
dc.creator Inanli, Ikbal Civi
dc.date 2014-02-28T22:00:00Z
dc.date.accessioned 2020-10-06T09:24:44Z
dc.date.available 2020-10-06T09:24:44Z
dc.identifier 0dc78619-688a-40a6-9df9-7f7f2f7d1fe6
dc.identifier 10.5455/bcp.20130313045200
dc.identifier https://avesis.sdu.edu.tr/publication/details/0dc78619-688a-40a6-9df9-7f7f2f7d1fe6/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/53238
dc.description Introduction: Aripiprazole is a partial agonist of dopamine D-2 and D-3 and serotonin 5-HT1A, 5-HT2c and 5-HT7 receptors, and it is also an antagonist of serotonin 5-HT2A and 5-HT6 receptors. Partial D-2 receptor agonism is thought to stabilize dopaminergic neurotransmission in the mesolimbic and mesocortical pathways. Dysregulation in the dopamine and serotonin systems is known to be one of the factors that is responsible for the etiology of depression. In this study, we aimed to evaluate the antidepressant potential of aripiprazole in rats by studying its effects on dopamine and serotonin receptors.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Evaluating The Antidepressant Efficacy of Aripiprazole Using a Chronic Mild Stress Model: An Experimental Study
dc.type info:eu-repo/semantics/article


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