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The role of endothelial glycocalyx in health and disease

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dc.creator Yilmaz, Onur
dc.creator Kanbay, Mehmet
dc.creator AFŞAR, Barış
dc.creator Ortiz, Alberto
dc.date 2019-09-30T21:00:00Z
dc.date.accessioned 2020-10-06T09:32:43Z
dc.date.available 2020-10-06T09:32:43Z
dc.identifier 2507fca5-1b1f-437d-bb0e-4552172bde73
dc.identifier 10.1093/ckj/sfz042
dc.identifier https://avesis.sdu.edu.tr/publication/details/2507fca5-1b1f-437d-bb0e-4552172bde73/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/55574
dc.description The endothelium is the largest organ in the body and recent studies have shown that the endothelial glycocalyx (eGCX) plays a major role in health and disease states. The integrity of eGCX is vital for homoeostasis and disruption of its structure and function plays a major role in several pathologic conditions. An increased understanding of the numerous pathophysiological roles of eGCX may lead to the development of potential surrogate markers for endothelial injury or novel therapeutic targets. This review provides a state-of-the-art update on the structure and function of the eGCX, emphasizing the current understanding of interorgan crosstalk between the eGCX and other organs that might also contribute to the pathogenesis of kidney diseases.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title The role of endothelial glycocalyx in health and disease
dc.type info:eu-repo/semantics/article

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