| dc.creator |
Alkan, Muzaffer |
|
| dc.creator |
Yuksek, Haydar |
|
| dc.creator |
Gursoy-Kol, Ozlem |
|
| dc.creator |
Calapoglu, Mustafa |
|
| dc.date |
2007-12-31T22:00:00Z |
|
| dc.date.accessioned |
2020-10-06T09:36:08Z |
|
| dc.date.available |
2020-10-06T09:36:08Z |
|
| dc.identifier |
2ac18fed-db3b-4e1b-9b15-6e18462d5740 |
|
| dc.identifier |
10.3390/molecules13010107 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/2ac18fed-db3b-4e1b-9b15-6e18462d5740/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/56149 |
|
| dc.description |
3-Alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones 2a-g reacted with 4-diethylaminobenzaldehyde to afford the corresponding 3-alkyl(aryl)-4-(4-diethylaminobenzylidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones 3a-g. The acetylation reactions of compounds 3a-e were investigated and compounds 4a-e were thus obtained. The new compounds were characterized using IR, H-1-NMR, C-13-NMR, UV and MS spectral data. In addition, the newly synthesized compounds 3a-g were titrated potentiometrically with tetrabutylammonium hydroxide in four non-aqueous solvents such as isopropyl alcohol, tert-butyl alcohol, acetone and N,N-dimethylformamide (DMF), and the half-neutralization potential values and the corresponding pK(a) values were determined for all cases. Moreover, 3 and 4 type compounds were also screened for their antioxidant activities. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Synthesis, acidity and antioxidant properties of some novel 3,4-disubstituted-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives |
|
| dc.type |
info:eu-repo/semantics/article |
|