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Central hemodynamics, vascular stiffness, and nocturia in patients with type 2 diabetes

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dc.creator Afsar, Barış
dc.creator Elsurer, Rengin
dc.date 2015-11-25T22:00:00Z
dc.date.accessioned 2020-10-06T09:39:14Z
dc.date.available 2020-10-06T09:39:14Z
dc.identifier 2f3039b8-07f4-41dc-b498-13019d719468
dc.identifier 10.3109/0886022x.2015.1088335
dc.identifier https://avesis.sdu.edu.tr/publication/details/2f3039b8-07f4-41dc-b498-13019d719468/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/56569
dc.description Recently, studies have shown that the presence of nocturia may not be a benign condition and related with systemic illness and mortality. Elevated blood pressure (BP) was another factor related with nocturia. Type 2 diabetes mellitus (T2DM) is also associated with nocturia. It is now clear that, apart from peripheral BP, central hemodynamic parameters are important for cardiovascular prognosis. However, no previous study in the literature examined the relationship between nocturia and central hemodynamic parameters in patients with T2DM. The current study was designed to examine these relationships. Nocturia was defined as two or more voids per night. Central hemodynamic parameters were assessed from ambulatory BP measurements. In addition to routine biochemistry, 24-h urine collection was performed to measure protein, albumin, and sodium excretion. 158 patients (52.3%) had T2DM and 144 (47.7%) did not have T2DM (control group). The presence of T2DM was independently related with nocturia. Both in whole group and in T2DM patients, most of the hemodynamic parameters are higher in patients with nocturia compared to patients without nocturia. Among patients with T2DM, nocturia was associated with augmentation index and pulse wave velocity. In conclusion, central hemodynamic parameters and markers of vascular stiffness may be related with nocturia in patients with T2DM.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Central hemodynamics, vascular stiffness, and nocturia in patients with type 2 diabetes
dc.type info:eu-repo/semantics/article


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