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Mean platelet volume is elevated in patients with heroin addiction

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dc.creator AKPINAR, Abdullah
dc.creator VAROL, Ercan
dc.creator Guven, Mukerrem
dc.creator Gecici, Omer
dc.creator Yalniz, Hacer
dc.date 2013-11-30T22:00:00Z
dc.date.accessioned 2020-10-06T09:43:36Z
dc.date.available 2020-10-06T09:43:36Z
dc.identifier 35c62964-7fe6-4fb0-adf0-27551fcdce4b
dc.identifier https://avesis.sdu.edu.tr/publication/details/35c62964-7fe6-4fb0-adf0-27551fcdce4b/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/57244
dc.description Increased cardiovascular risk have been reported in heroin abuse. It has been suggested that multiple mechanisms may be involved in the relationship between heroin abuse and cardiovascular risk; these include hypoxia, vasculitis and vasospasm. In some studies increased platelet aggregation and morphological changes have also been reported in heroin addicts. Mean platelet volume (MPV) is an indicator of platelet reactivity and it plays an important role in the pathophysiology of cardiovascular diseases. The aim of this study was to investigate MPV values in heroin addicts. We measured serum MPV values in heroin addicts and control subjects. MPV was significantly higher among heroin addicts than in the control group(8.6+/-1.1 vs. 7.8+/-0.7 fL respectively; p<0.001). In correlation analysis, there was correlation between duration of heroin use and MPV (r:-0,09 p:0.32). We have found that MPV was elevated in heroin addicts.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Mean platelet volume is elevated in patients with heroin addiction
dc.type info:eu-repo/semantics/article


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