| dc.creator |
NUROZLER, Ayse Burcu |
|
| dc.creator |
Ergun, Gul |
|
| dc.creator |
Kocaoglu, Fatma Akbas |
|
| dc.creator |
DUMAN, Sunay |
|
| dc.creator |
Tok, Ozlem Yalcin |
|
| dc.date |
2007-12-31T22:00:00Z |
|
| dc.date.accessioned |
2020-10-06T09:47:57Z |
|
| dc.date.available |
2020-10-06T09:47:57Z |
|
| dc.identifier |
3cc86682-1dc6-4a2a-b5d7-95689f4cd15d |
|
| dc.identifier |
10.1159/000151740 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/3cc86682-1dc6-4a2a-b5d7-95689f4cd15d/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/57939 |
|
| dc.description |
Aims: To investigate the efficacy and safety of postoperative topical cyclosporine A 0.05% (tCsA) (Restasis (R), Allergan Pharmaceutical) eye drops in preventing the recurrence of pterygium. Methods: 31 patients with bilateral pterygium were examined between January 2006 and February 2007. During a 1-year follow-up, the right eyes of the patients assigned as the treatment group were treated by tCsA and the left eyes were considered as the control group. Results: The pterygium recurred in 4 (12.9%) of 31 right eyes in the treatment group and in 14 (45.2%) of 31 left eyes in the control group (p = 0.005). The mean follow-up +/- SD was 9.39 +/- 4.14 months (range, 1 to 12 months). The control group had a 7.37 times higher risk of recurrence in pterygium compared with the treatment group (OR = 0.1357, p = 0.0051). A statistically significant difference in recurrence-free probabilities was found for the treatment and control groups (log-rank test; p = 0.006). A multivariate Cox regression model showed that age (p = 0.0093) and tCsA (p = 0.0103) were independent statistically significant impacts on recurrence-free time for pterygium. Conclusion: This study suggests that primary excision of pterygium with postoperative instillation of 0.05% cyclosporine is both safe and efficient. Copyright (C) 2008 S. Karger AG, Basel |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Topical Cyclosporine A in the Prevention of Pterygium Recurrence |
|
| dc.type |
info:eu-repo/semantics/article |
|