| dc.creator |
Islek, Ali |
|
| dc.creator |
Sayar, Ersin |
|
| dc.creator |
YILMAZ, AYGEN |
|
| dc.creator |
Flanagan, Sarah E. |
|
| dc.creator |
ARTAN, REHA |
|
| dc.creator |
AKÇAM, Mustafa |
|
| dc.date |
2013-09-30T21:00:00Z |
|
| dc.date.accessioned |
2020-10-06T09:48:13Z |
|
| dc.date.available |
2020-10-06T09:48:13Z |
|
| dc.identifier |
3ebee3ed-b76d-4e59-a623-7e0115a9aab8 |
|
| dc.identifier |
10.1111/ped.12169 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/3ebee3ed-b76d-4e59-a623-7e0115a9aab8/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/58136 |
|
| dc.description |
Congenital diarrheal disorders consist of a variety of chronic enteropathies. There are approximately 30 different diseases that can be classified into four groups according to the mechanisms involved in pathogenesis: (i) absorption and transport of nutrients and electrolytes; (ii) enterocyte differentiation and polarization; (iii) enteroendocrine cell differentiation; and (iv) modulation of the intestinal immune response. Affected patients often present with life-threatening diarrhea, in the first few weeks of life. A new disorder, enteric anendocrinosis, which is characterized by severe malabsorptive diarrhea and a lack of intestinal enteroendocrine cells has recently been described in six patients with recessively inherited mutations in the Neurogenin-3 gene. In this report we describe a seventh case with a review of the literature. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Extremely rare cause of congenital diarrhea: Enteric anendocrinosis |
|
| dc.type |
info:eu-repo/semantics/article |
|