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Benzimidazolium-based novel silver N-heterocyclic carbene complexes: synthesis, characterisation and in vitro antimicrobial activity

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dc.creator Sari, Yakup
dc.creator Akkoc, Senem
dc.creator GÖK, YETKİN
dc.creator Sifniotis, Vicki
dc.creator ÖZDEMİR, İLKNUR
dc.creator GÜNAL, SELAMİ
dc.creator Kayser, Veysel
dc.date 2015-12-31T22:00:00Z
dc.date.accessioned 2020-10-06T09:48:13Z
dc.date.available 2020-10-06T09:48:13Z
dc.identifier 3ecc6fbb-9020-44ae-9216-bb2b54af7ad1
dc.identifier 10.3109/14756366.2016.1156102
dc.identifier https://avesis.sdu.edu.tr/publication/details/3ecc6fbb-9020-44ae-9216-bb2b54af7ad1/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/58144
dc.description This study reports the synthesis, characterisation and antimicrobial activity of five novel silver N-heterocyclic carbene (Ag-NHC) complexes obtained by N-propylphthalimide and N-methyldioxane substituted benzimidazolium salts with silver oxide. The reactions were performed at room temperature for 24 h in the absence of light. The obtained complexes were identified and characterised by H-1 and C-13 NMR, FT-IR and elemental analysis techniques. The minimum inhibitory concentration (MIC) of the complexes was determined for E. coli, P. aeruginosa, E. faecalis, S. aureus, C. tropicalis and C. albicans in vitro through agar and broth dilution. The results indicated that these complexes exhibit antimicrobial activity. In particular, complex 3 presented the significant broad spectrum antimicrobial activity.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Benzimidazolium-based novel silver N-heterocyclic carbene complexes: synthesis, characterisation and in vitro antimicrobial activity
dc.type info:eu-repo/semantics/article


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