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Can we Predict Preoperative Tumor Aggressivity with Hemogram Parameters in Renal Cell Carcinoma? a Novel Calculation Method

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dc.creator UÇAR, MURAT
dc.creator Soyupek, Sedat
dc.creator OKSAY, Taylan
dc.creator Akkoc, Ali
dc.creator ÖZORAK, Alper
dc.creator Topcuoglu, Murat
dc.creator DEMİR, Murat
dc.creator KOŞAR, Alim
dc.date 2019-12-09T21:00:00Z
dc.date.accessioned 2020-10-06T09:49:49Z
dc.date.available 2020-10-06T09:49:49Z
dc.identifier 4a90bf72-6e89-4fd5-9d6c-8f24e61bc42b
dc.identifier 10.1007/s10916-019-1491-2
dc.identifier https://avesis.sdu.edu.tr/publication/details/4a90bf72-6e89-4fd5-9d6c-8f24e61bc42b/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/59348
dc.description We aim to investigate the prognostic significance of the hemoglobin X lymphocyte / neutrophil ratio (HLNR) and hemoglobin x lymphocyte / platelet ratio (HLPR) with tumor aggressivity in patients with renal cell carcinoma. We retrospectively analyzed 127 patients' data who had diagnosed as renal cell carcinoma between 2008 and 2019 in Suleyman Demirel University Hospital. Tumor and patient characteristics, hemoglobin, neutrophil, lymphocyte, platelet values HLNR and HLPR were calculated in preoperative hemogram parameters. The relationship between tumor pathological stage, Fuhrman nuclear grade and tumor necrosis with HLPR and HLNR analyzed with statistically. There was a negative correlation between pathologic stage, Fuhrman nuclear grade and tumor necrosis with HLNR. P values are 0.003, 0.012 and 0.015 respectively. HLNR was lower in patients with high pathologic stage, high Fuhrman nuclear grade and accompanying tumor necrosis positiveness. There was a negative correlation between pathologic stage, Fuhrman nuclear grade and tumor necrosis with HLPR. P values are 0.001, 0.014 and 0.047 respectively. HLPR was lower in patients with high pathologic stage, high Fuhrman nuclear grade and accompanying tumor necrosis positiveness. High pathological stage, high Fuhrman nuclear grade and existence of tumor necrosis are associates with preoperative low HLNR and low HLPR in renal cell carcinoma patients. They can be used as prognostic markers in patients with renal mass preoperatively.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Can we Predict Preoperative Tumor Aggressivity with Hemogram Parameters in Renal Cell Carcinoma? a Novel Calculation Method
dc.type info:eu-repo/semantics/article


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