| dc.creator |
KARAHAN, Nermin |
|
| dc.creator |
Yariktas, Murat |
|
| dc.creator |
Kapucuoglu, Nilgun |
|
| dc.creator |
Baspinar, Şirin |
|
| dc.date |
2008-12-31T22:00:00Z |
|
| dc.date.accessioned |
2020-10-06T09:50:12Z |
|
| dc.date.available |
2020-10-06T09:50:12Z |
|
| dc.identifier |
4d84d025-8725-4a2e-8153-30f0dd739a78 |
|
| dc.identifier |
10.1016/j.jvoice.2007.05.005 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/4d84d025-8725-4a2e-8153-30f0dd739a78/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/59647 |
|
| dc.description |
The objective Of this Study was to investigate the roles of matrix metalloproteinases (MMP-2, MMP-9) and cyclooxygenase-2 (COX-2) in the pathogenesis of vocal fold polyps (VFPs). Ill this study, 20 VFPs and 8 normal vocal fold (VF) specimens were obtained from subjects undergoing surgery. Staining intensities were semiquantitatively assessed and statistically analyzed. Significant increases were observed ill the expressions of MMP-2, MMP-9. and COX-2 ill stromal spindle cells (P = 0.00) and vascular wall (P = 0.04, P = 0.00, P = 0.00) of VFPs compared with normal VFs. MMP-2 expression ill surface epithelium basal cells (P = 0.00) of VFPs showed enhancement compared with normal vocal folds. whereas MMP-9 and COX-2 expressions showed no significant differences. Our study showed that gelatinases and COX-2 may play a role in the development of VFPs, This is the first Study to document the expression Of gelatinases and COX-2 in VFPs. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Matrix Metalloproteinases (MMP-2 and MMP-9) and cyclooxygenase-2 (COX-2) expressions in vocal fold polyps. |
|
| dc.type |
info:eu-repo/semantics/article |
|