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Aortic Elasticity is Impaired in Patients with Endemic Fluorosis

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dc.creator VAROL, Ercan
dc.creator AKCAY, Selahattin
dc.creator ERSOY, I. Hakki
dc.creator KOROGLU, Banu Kale
dc.creator Ozaydin, Mehmet
dc.creator Varol, Simge
dc.date 2010-01-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:14:24Z
dc.date.available 2020-10-06T10:14:24Z
dc.identifier 561cfc23-77b1-4510-b0b3-1453d877028b
dc.identifier 10.1007/s12011-009-8578-4
dc.identifier https://avesis.sdu.edu.tr/publication/details/561cfc23-77b1-4510-b0b3-1453d877028b/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/60507
dc.description Sixty-three patients with endemic fluorosis (36 males/27 females; mean age 33.9 +/- 8.6 years) and 45 age-, sex-, and body mass index-matched healthy controls (30 males/15 females; mean age 32.7 +/- 8.8 years) were included in this study. Aortic stiffness indices, aortic strain (AS), aortic distensibility (AD), and aortic strain index (ASI) were calculated from the aortic diameters measured by echocardiography and blood pressure obtained by sphygmomanometry. The urine fluoride levels of fluorosis patients were significantly higher than control subjects as expected (1.9 +/- 0.1 mg/l vs. 0.4 +/- 0.1 mg/l, respectively; P < 0.001). AS and AD were significantly lower in fluorosis patients than in the controls (for AS 5.3 +/- 3.6 vs. 8.0 +/- 3.4%; P < 0.001 and for AD 0.2 +/- 0.1 vs. 0.3 +/- 0.1 cm(2) dyn(-1) 10(-3); P < 0.001, respectively). In contrast, signicantly higher ASI was observed in fluorosis patients than in the controls (3.4 +/- 0.6 vs. 3.0 +/- 0.4; P < 0.001, respectively). The results of our study demonstrate that elastic properties of ascending aorta are impaired in patients with endemic fluorosis.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Aortic Elasticity is Impaired in Patients with Endemic Fluorosis
dc.type info:eu-repo/semantics/article


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