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Mean platelet volume, an indicator of platelet activation, is increased in patients with mitral stenosis and sinus rhythm

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dc.creator VAROL, Ercan
dc.creator Ozaydin, Mehmet
dc.creator Turker, Yasin
dc.creator ALACA, Sule
dc.date 2008-12-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:14:36Z
dc.date.available 2020-10-06T10:14:36Z
dc.identifier 57aae490-d8da-422b-be60-39366463cecc
dc.identifier 10.1080/00365510903007000
dc.identifier https://avesis.sdu.edu.tr/publication/details/57aae490-d8da-422b-be60-39366463cecc/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/60661
dc.description Systemic thromboembolism is a serious major complication in patients with mitral stenosis. However, the pathogenesis of thromboembolism in mitral stenosis is not fully understood. Previous studies have demonstrated that platelet activation occurs in serum of patients with rheumatic mitral stenosis (MS). The aim of this study was to assess the mean platelet volume (MPV), an indicator of platelet activation, in patients with MS. The study group consisted of 36 patients with MS who were in sinus rhythm. An age and gender matched control group was composed of 30 healthy volunteers. We measured serum MPV values in patients and control subjects. MPV was significantly higher among MS patients with sinus rhythm (SR) when compared with the control group (9.2 +/- 1.4 vs 8.1 +/- 0.9 fl respectively; p0.001). We have shown that MPV was significantly elevated in patients with MS who were in SR compared to control subjects.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Mean platelet volume, an indicator of platelet activation, is increased in patients with mitral stenosis and sinus rhythm
dc.type info:eu-repo/semantics/article


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