| dc.creator |
MENDİ, Mehmet Ali |
|
| dc.creator |
Afsar, Barış |
|
| dc.creator |
OKSUZ, Fatih |
|
| dc.creator |
TURAK, Osman |
|
| dc.creator |
YAYLA, Cagri |
|
| dc.creator |
Johnson, Richard J. |
|
| dc.creator |
OZCAN, Firat |
|
| dc.creator |
Kanbay, Mehmet |
|
| dc.date |
2017-07-31T21:00:00Z |
|
| dc.date.accessioned |
2020-10-06T10:25:50Z |
|
| dc.date.available |
2020-10-06T10:25:50Z |
|
| dc.identifier |
68426f56-833f-40d8-bd59-03bdd727049f |
|
| dc.identifier |
10.1177/0003319716639187 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/68426f56-833f-40d8-bd59-03bdd727049f/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/62336 |
|
| dc.description |
Developing contrast-induced nephropathy (CIN) after primary percutaneous coronary intervention (pPCI) has a negative impact on survival and morbidity. We assessed the predictive value of serum uric acid (SUA) for the development of CIN in patients with ST-segment elevation myocardial infarction (STEMI) who underwent pPCI. Contrast-induced nephropathy was defined an increase of 25% or 0.5 mg/dL in creatinine concentrations within 72 hours after pPCI. Patients were divided into 2 groups according to admission median SUA level. Serum uric acid level was <5.4 mg/dL (group 1; n = 222) and 5.4 mg/dL (group 2; n = 228). Compared to group 1, development of CIN (12% vs 20%, P < .001) was significantly greater in group 2. Using a cut point of >5.45 mg/dL, the SUA level predicted development of CIN with a sensitivity of 70% and specificity of 67%. In multiple logistic regression analysis, SUA level, diabetes mellitus, left ventricular ejection fraction <50%, contrast volume, estimated glomerular filtration rate, and C-reactive protein level emerged as independent predictors of CIN. In conclusion, elevated SUA is an independent risk factor for the development of CIN after pPCI in patients with STEMI. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Uric Acid is a Useful Tool to Predict Contrast-Induced Nephropathy |
|
| dc.type |
info:eu-repo/semantics/article |
|