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Utility of serum creatinine/cystatin C ratio in diagnosis of postrenal acute kidney injury

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dc.creator ÖZORAK, Alper
dc.creator Inal, Salih
dc.creator ALTUNTAŞ, Atila
dc.creator Kidir, Veysel
dc.creator Ilgin, Yusuf
dc.creator Sezer, Mehmet Tugrul
dc.date 2014-10-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:31:14Z
dc.date.available 2020-10-06T10:31:14Z
dc.identifier 6b2bf5eb-fd5e-49b4-a5d8-1b4b199c1b1c
dc.identifier https://avesis.sdu.edu.tr/publication/details/6b2bf5eb-fd5e-49b4-a5d8-1b4b199c1b1c/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/62628
dc.description Background: In obstructive uropathy, despite a severe increase in the serum creatinine (Cr) levels, only a mild cystatin C (CysC) increase was previously reported. Therefore, we aimed to determine the availability of serum Cr/CysC ratio in predicting postrenal acute kidney injury (AKI). Materials and Methods: This was a cross-sectional study involving 61-adult patients with heterogeneous AKI cases. Patients with bilateral pelvicalyceal dilatation in renal sonography were considered as postrenal AKI group (n = 15) and others were intrinsic AKI group (n = 46). Venous blood sampling for blood urea nitrogen, Cr and CysC measurements were performed on admission. Results: The mean age of study population was 66.3 +/- 15.5 years; 38 (62%) of which were male. Two groups were similar regarding age, gender, and comorbidities. Cr/CysC ratio was significantly higher in postrenal AKI group (6.9 +/- 3.1 vs. 4.4 +/- 2.1, P = 0.007). Conclusion: We suggest that serum Cr/CysC ratio seems to be a useful diagnostic tool for detection of postrenal AKI cases, especially for the cases without definite hydronephrosis.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Utility of serum creatinine/cystatin C ratio in diagnosis of postrenal acute kidney injury
dc.type info:eu-repo/semantics/article


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