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Autoimmune hemolytic anemia during interferon-beta-1b treatment for multiple sclerosis

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dc.creator Kilbas, S.
dc.creator ARSLAN, ÇAĞTAY
dc.creator Kutluhan, Süleyman
dc.creator Alanoglu, G.
dc.creator Senol, Altuğ
dc.date 2007-05-31T21:00:00Z
dc.date.accessioned 2020-10-06T10:31:31Z
dc.date.available 2020-10-06T10:31:31Z
dc.identifier 6d5c6d12-2efe-41bd-a9eb-d101d5ac8359
dc.identifier 10.1177/1352458506071333
dc.identifier https://avesis.sdu.edu.tr/publication/details/6d5c6d12-2efe-41bd-a9eb-d101d5ac8359/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/62849
dc.description A 31 -year-old patient with multiple sclerosis (MS), treated with interferon beta-1 b (IFNB-1 b) for two years, presented with fatigue and dizziness. Coombs' positive autoimmune hemolytic anemia (AIHA) was found. Other potential etiologies of ANA were ruled out. An association with IFNB-1 b was highly suspected. Interferon therapy was discontinued and prednisone therapy instituted. There was resolution of the hemolytic anemia, and prednisone therapy was tapered gradually. To the best of our knowledge, there is no reported case of the development of ANA associated with IFNB-1 b use in MS patients. We conclude that if an unexplained drop in hematocrit occurs with a MS patient receiving IFNB-1 b, autoimmune mediated hemolysis should also be considered.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Autoimmune hemolytic anemia during interferon-beta-1b treatment for multiple sclerosis
dc.type info:eu-repo/semantics/article


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