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Erythropoietin mediates brain-vascular-kidney crosstalk and may be a treatment target for pulmonary and resistant essential hypertension

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dc.creator Onal, Emine Meltem
dc.creator Sag, Alan Alper
dc.creator Sal, Oguzhan
dc.creator AFŞAR, Barış
dc.creator Yerlikaya, Aslihan
dc.creator Kanbay, Mehmet
dc.date 2016-12-31T21:00:00Z
dc.date.accessioned 2020-10-06T10:31:55Z
dc.date.available 2020-10-06T10:31:55Z
dc.identifier 70afafaa-4050-4255-8fc9-91fa03973ab1
dc.identifier 10.1080/10641963.2016.1246565
dc.identifier https://avesis.sdu.edu.tr/publication/details/70afafaa-4050-4255-8fc9-91fa03973ab1/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/63154
dc.description Organ crosstalk pathways represent the next frontier for target-mining in molecular medicine for existing syndromes. Pulmonary hypertension and resistant essential hypertension are syndromes that have been proven elusive in etiology, and frequently refractory to first-line management. Underlying crosstalk mechanisms, not yet considered in these treatments, may hinder outcomes or unlock novel treatments. This review focuses systematically on erythropoietin, a synthesizable molecule, as a mediator of brain-kidney crosstalk. Insights gained from this review will be applied to cardiovascular diseases in a clinician-directed fashion.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Erythropoietin mediates brain-vascular-kidney crosstalk and may be a treatment target for pulmonary and resistant essential hypertension
dc.type info:eu-repo/semantics/article


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