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Catecholase-Like Activity Studies of Tc-99m Radiopharmaceuticals

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dc.creator Cicek, E.
dc.creator DEDE, Bülent
dc.date 2016-01-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:40:03Z
dc.date.available 2020-10-06T10:40:03Z
dc.identifier 7e90c124-ec16-4492-bce5-7d8e80a36de1
dc.identifier 10.12693/aphyspola.129.213
dc.identifier https://avesis.sdu.edu.tr/publication/details/7e90c124-ec16-4492-bce5-7d8e80a36de1/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/64529
dc.description Catechol oxidase catalyses the oxidation of a broad range of catechols to the corresponding o-quinones through the four-electron reduction of molecular oxygen to water, without acting on tyrosine. The resulting highly reactive quinones autopolymerize to form brown polyphenolic catechol melanins, a process thought to protect the damaged plant against pathogens or insects. This work describes the catalytic activity of some radiopharmaceuticals like Tc-99m pertechnetate, Tc-99m mercaptoacetyltriglycine (MAG3), Tc-99m nanocolloid, Tc-99m methylenebis(phosphonic acid) (MDP) and Tc-99m methoxyisobutylisonitrile (MIBI) for oxidation of catechol. The catalytic oxidation of 3,5-di-tert-butylcatechol by selected radiopharmaceuticals saturated with molecular oxygen was studied in a homogeneous system. All the radiopharmaceuticals exhibited catecholase-like activity.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Catecholase-Like Activity Studies of Tc-99m Radiopharmaceuticals
dc.type info:eu-repo/semantics/article


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