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Feasibility Study of Using Breath Ammonia Analysis Based on Off-Axis Cavity-Enhanced Absorption Spectroscopy with External Cavity Diode Laser for Noninvasive Real-Time Diagnosis of Helicobacter Pylori

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dc.creator Bayrakli, Ismail
dc.creator KOÇKAR, Muhammet Cem
dc.creator Turkmen, Aysenur
dc.date 2016-07-31T21:00:00Z
dc.date.accessioned 2020-10-06T10:40:04Z
dc.date.available 2020-10-06T10:40:04Z
dc.identifier 7eba280b-a00f-437e-80ca-f2f00903731e
dc.identifier 10.1177/0003702816654052
dc.identifier https://avesis.sdu.edu.tr/publication/details/7eba280b-a00f-437e-80ca-f2f00903731e/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/64547
dc.description The purpose of this study is to assess the feasibility of using breath ammonia analysis based on off-axis cavity-enhanced absorption spectroscopy (OA-CEAS) with an external-cavity diode laser (ECL) for noninvasive, real-time diagnosis of Helicobacter pylori (HP) infection. Analyses are performed for the breath of 15 healthy volunteers, and eight children and 19 adults with HP infection. The range of ammonia levels for healthy participants is determined to be between 178 and 610ppb, whereas the ranges for child and adult patients with HP infection are measured to be 457-2470ppb and 450-2990ppb, respectively. The ammonia concentrations for patients with HP infection are significantly higher than the concentrations for healthy volunteers. However, no sharp boundary between the ammonia concentrations in the breath of patients with HP infection and healthy volunteers is observed. No correlation between breath ammonia and either body mass index (BMI) or age is found. The reported results suggest that our breath ammonia measurement system has the potential for future use in easy, noninvasive diagnosis of HP infection.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Feasibility Study of Using Breath Ammonia Analysis Based on Off-Axis Cavity-Enhanced Absorption Spectroscopy with External Cavity Diode Laser for Noninvasive Real-Time Diagnosis of Helicobacter Pylori
dc.type info:eu-repo/semantics/article


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