| dc.creator |
EVİRGEN, OYA |
|
| dc.creator |
Ozguner, Meltem |
|
| dc.creator |
Oral, Baha |
|
| dc.date |
2009-06-29T21:00:00Z |
|
| dc.date.accessioned |
2020-10-06T10:40:15Z |
|
| dc.date.available |
2020-10-06T10:40:15Z |
|
| dc.identifier |
8040ca29-eed1-498f-801e-c674f12c87fc |
|
| dc.identifier |
10.3349/ymj.2009.50.3.352 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/8040ca29-eed1-498f-801e-c674f12c87fc/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/64692 |
|
| dc.description |
Purpose: A prospective study was planned to determine the relationship between post swim-up acrosome index (AI) evaluation and fertilization outcomes in an in vitro fertilization (IVF) program. Materials and Methods: Infertile couples who have applied to IVF were admitted into this study when the male partner's sperm concentration was > 20 x 10(6)/mL and motility > 30%. Pre- and post swim-up semen quality parameters including concentration, motility, sperm morphology and AI were evaluated in a prospective, randomized and blinded fashion. The couples were divided prospectively into 2 groups. In group I (25 couples) 50 000 sperm per oocyte were used for insemination considering post swim-up acrosome index, and in group II (25 couples) 50 000 sperm per oocyte were used for insemination without considering post swim-up acrosome index. Results: Pre- and post swim-up AI were 30.8 +/- 3.4 and 17.8 +/- 4.5 in group I, and 31.4 +/- 3.6 and 16.3 +/- 4.7 in group II (p > 0.05) respectively. The significant improvement in morphology and motility after double wash swim-up procedure has been observed. However, double wash swim-up procedure could not eliminate head and especially acrosomal defects which would directly effect fertilization capacity in conventional IVF program. In group I, 85.3% of oocytes were fertilized, with a 48% pregnancy rate; in group II, 71.0% of oocytes were fertilized, with a pregnancy rate of 20%. Fertilization and pregnancy rates were significantly different (p < 0.05) between the two groups. Conclusion: We have concluded that it could be useful to consider post swim-up AI of sperm inseminated in conventional IVF cycles, which correlates with high fertilization and pregnancy rates. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Correlation of Post Swim-Up Acrosome Index with in-vitro Fertilization Outcomes |
|
| dc.type |
info:eu-repo/semantics/article |
|