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Topical Ophthalmic Cyclosporine in the Treatment of Toxic Epidermal Necrolysis

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dc.creator Kocak, Mukadder
dc.creator Ornek, Kemal
dc.creator Usta, Gülşah
dc.creator Buyukkocak, Unase
dc.creator Onaran, Zafer
dc.date 2010-12-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:47:23Z
dc.date.available 2020-10-06T10:47:23Z
dc.identifier 8728d3e0-d30a-448d-a521-eb4c58beee34
dc.identifier 10.1155/2011/416842
dc.identifier https://avesis.sdu.edu.tr/publication/details/8728d3e0-d30a-448d-a521-eb4c58beee34/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/65394
dc.description Aim. To describe a case of toxic epidermal necrolysis (TEN) with ocular involvement treated with topical ophthalmic cyclosporine. Case Presentation. A 20-year-old woman developed TEN following administration of carbamazepine that was prescribed for epilepsy. Ophthalmic examination revealed bilateral pseudomembranous conjunctivitis. She was hospitalized in the intensive care unit and treated with intravenous corticosteroid and immunoglobulin. Topical cyclosporine was used in combination with topical corticosteroids for ocular surface disease. Following two months of ocular treatment, she recovered without any severe ocular complication. Ocular examination at the four-month followup showed a 2mm of symblepharon in the lower fornix as the sole pathologic finding. Conclusion. Topical ophthalmic cyclosporine may contribute to decrease the ophthalmic complications of TEN and should be considered in the acute stage of the disease.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Topical Ophthalmic Cyclosporine in the Treatment of Toxic Epidermal Necrolysis
dc.type info:eu-repo/semantics/article


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