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A novel amperometric glucose biosensor based on poly(glycidyl methacrylate-co-(3-thienylmethylmethacrylate))

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dc.creator Karagollu, Osman
dc.creator Gorur, Mesut
dc.creator Sengez, Busra
dc.creator YILMAZ, FARUK
dc.creator GÖDE, Fethiye
dc.creator TÜRKAN, ALİ
dc.date 2013-05-31T21:00:00Z
dc.date.accessioned 2020-10-06T10:48:09Z
dc.date.available 2020-10-06T10:48:09Z
dc.identifier 8cf9d1ca-3f8b-48ba-9f0a-954b7cdc47aa
dc.identifier 10.1016/j.cap.2012.11.013
dc.identifier https://avesis.sdu.edu.tr/publication/details/8cf9d1ca-3f8b-48ba-9f0a-954b7cdc47aa/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/65972
dc.description Two novel glucose oxidase (GOx) enzyme electrodes based on the copolymer of glycidyl methacrylate with 3-thienylmethyl methacrylate (poly(GMA-co-MTM)) with and without polypyrrole (PPyr) coating were prepared and employed in the amperometric determination of glucose levels. The effect of PPyr coating on the electrode properties was investigated in detail. Cyclic voltammetry studies showed that electrical conductivity of electrode B with PPyr coating (poly(GMA-co-MTM)/GOx/PPyr) was substantially higher than that of electrode A (poly(GMA-co-MTM)/GOx). On the other hand, electrode A showed better results in terms of sensitivity (10 nA/mM), limit of detection (50.2 mu M), and response time (5 s). Electrodes A and B gave linear responses to the glucose concentrations in the range of 2-20 and 2-14 mM, respectively. The ranges of linearity for both enzyme electrodes are sufficient for the determination of physiological glucose concentrations in human blood. Moreover, PPyr coating of electrode B did not result in further stabilization of the enzyme electrode. (C) 2012 Elsevier B.V. All rights reserved.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title A novel amperometric glucose biosensor based on poly(glycidyl methacrylate-co-(3-thienylmethylmethacrylate))
dc.type info:eu-repo/semantics/article


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