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Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices

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dc.creator OKSAY, Taylan
dc.creator NAZIROĞLU, Mustafa
dc.creator Dogan, S.
dc.creator Guzel, A.
dc.creator GÜMRAL, Nurhan
dc.creator Kosar, P. A.
dc.date 2014-01-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:48:11Z
dc.date.available 2020-10-06T10:48:11Z
dc.identifier 8d47ce3e-b80b-4e93-96e4-10f440a5cf53
dc.identifier 10.1111/and.12044
dc.identifier https://avesis.sdu.edu.tr/publication/details/8d47ce3e-b80b-4e93-96e4-10f440a5cf53/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/66005
dc.description Wireless devices have become part of everyday life and mostly located near reproductive organs while they are in use. The present study was designed to determine the possible protective effects of melatonin on oxidative stress-dependent testis injury induced by 2.45-GHz electromagnetic radiation (EMR). Thirty-two rats were equally divided into four different groups, namely cage control (A1), sham control (A2), 2.45-GHz EMR (B) and 2.45-GHz EMR+melatonin (C). Group B and C were exposed to 2.45-GHz EMR during 60minday(-1) for 30days. Lipid peroxidation levels were higher in Group B than in Group A1 and A2. Melatonin treatment prevented the increase in the lipid peroxidation induced by EMR. Also reduced glutathione (GSH) and glutathione peroxidase (GSH-Px) levels in Group D were higher than that of exposure group. Vitamin A and E concentrations decreased in exposure group, and melatonin prevented the decrease in vitamin E levels. In conclusion, wireless (2.45 GHz) EMR caused oxidative damage in testis by increasing the levels of lipid peroxidation and decreasing in vitamin A and E levels. Melatonin supplementation prevented oxidative damage induced by EMR and also supported the antioxidant redox system in the testis.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices
dc.type info:eu-repo/semantics/article


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