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Synthesis and biological evaluation of optically active conjugated gamma- and delta-lactone derivatives

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dc.creator Sardan, Melis
dc.creator Akkaya, Mahinur
dc.creator TANYELİ, CİHANGİR
dc.creator Sezer, Serdar
dc.creator Gunel, Aslihan
dc.date 2012-09-14T21:00:00Z
dc.date.accessioned 2020-10-06T10:48:53Z
dc.date.available 2020-10-06T10:48:53Z
dc.identifier 92798420-7b22-4031-87cd-ef95462f57c8
dc.identifier 10.1016/j.bmcl.2012.07.090
dc.identifier https://avesis.sdu.edu.tr/publication/details/92798420-7b22-4031-87cd-ef95462f57c8/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/66507
dc.description An efficient synthesis of racemic and both enantiomeric forms of heteroaryl substituted gamma- and delta-lactone derivatives derived from allyl and homoallyl alcohol backbones has been accomplished via ring closing metathesis reaction. 2-Heteroaryl substituted allyl and homoallyl alcohols have been efficiently resolved through enzymatic method with high ee (97-99%) and known stereochemistry. Antimicrobial and antioxidant activities of target lactones were evaluated. (C) 2012 Elsevier Ltd. All rights reserved.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Synthesis and biological evaluation of optically active conjugated gamma- and delta-lactone derivatives
dc.type info:eu-repo/semantics/article


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