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The effect of chronic kidney disease on lipid metabolism

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dc.creator Dincer, Neris
dc.creator Dagel, Tuncay
dc.creator AFŞAR, Barış
dc.creator ORTİZ, Alberto
dc.creator Kanbay, Mehmet
dc.creator COVİC, Adrian
dc.date 2019-01-31T21:00:00Z
dc.date.accessioned 2020-10-06T10:49:03Z
dc.date.available 2020-10-06T10:49:03Z
dc.identifier 93a146be-0b12-4235-90f3-bdeca1c0b668
dc.identifier 10.1007/s11255-018-2047-y
dc.identifier https://avesis.sdu.edu.tr/publication/details/93a146be-0b12-4235-90f3-bdeca1c0b668/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/66634
dc.description The major cause of death among chronic kidney disease patients is cardiovascular diseases. Cardiovascular and kidney disease are interrelated and increase the severity of each other. Dyslipidemia is one the major causes of cardiovascular disease among chronic kidney disease patients along with diabetes and hypertension. The relationship between dyslipidemia and chronic kidney disease is reciprocal. Dyslipidemia is known to be a risk factor for chronic kidney disease and chronic kidney disease causes major alterations on lipoprotein profile, defined as the dyslipidemic profile of chronic kidney disease patients. Increased triglyceride, very low density lipoprotein and oxidized low density lipoprotein as well as decreased high density lipoprotein and changes in the composition of lipoproteins contribute to the dyslipidemic profile. Treatment strategies targeting the dyslipidemic profile of chronic kidney disease could contribute to prevent cardiovascular diseases. Current therapy is based on the patient kidney function and consist mainly of statins. This review focuses on the effects of chronic kidney disease on the lipoprotein profile and how this may impact novel therapeutic approaches to cardiovascular risk.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title The effect of chronic kidney disease on lipid metabolism
dc.type info:eu-repo/semantics/article


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