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Mean Platelet Volume Is Increased in Infective Endocarditis and Decreases after Treatment

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dc.creator ARSLAN, Akif
dc.creator Icli, Atilla
dc.creator TAYYAR, Senol
dc.creator VAROL, Ercan
dc.creator AKSOY, Fatih
dc.creator ERSOY, Ibrahim
dc.creator AKCAY, Selahaddin
dc.date 2012-12-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:49:03Z
dc.date.available 2020-10-06T10:49:03Z
dc.identifier 93a1d71f-de44-4242-ae79-298c614f1278
dc.identifier 10.1159/000345393
dc.identifier https://avesis.sdu.edu.tr/publication/details/93a1d71f-de44-4242-ae79-298c614f1278/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/66635
dc.description Objectives: The aim of this study was to assess the mean platelet volume (MPV), an indicator of platelet activation in patients with infective endocarditis. Subjects and Methods: Twenty-nine patients with infective endocarditis and 29 healthy subjects were studied. Plasma MPV values in patients and control subjects were measured on admission and after 2 weeks of specific treatment of infective endocarditis. Results: The MPV was significantly higher among patients with infective endocarditis when compared with the control group (9.86 +/- 1.1 vs. 8.0 +/- 1.0 fl, respectively; p < 0.01). The MPV values of patients with infective endocarditis decreased significantly after treatment from 9.86 +/- 1.1 to 7.86 +/- 1.0 fl (p < 0.01). Total platelet counts increased significantly after treatment from 193.4 +/- 96.5 x 10(9) to 243.7 +/- 92.4 x 10(9) (p = 0.04). Conclusion: MPV values were higher in patients with infective endocarditis and decreased significantly after treatment. Elevated MPV values indicate that patients with infective endocarditis have increased platelet activation and infective endocarditis treatment decreases this platelet activation by decreasing MPV. Copyright (C) 2012 S. Karger AG, Basel
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Mean Platelet Volume Is Increased in Infective Endocarditis and Decreases after Treatment
dc.type info:eu-repo/semantics/article


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