| dc.creator |
Celik, Gamze |
|
| dc.creator |
ÖKSÜZ, Ayşegül |
|
| dc.date |
2015-01-01T22:00:00Z |
|
| dc.date.accessioned |
2020-10-06T10:49:50Z |
|
| dc.date.available |
2020-10-06T10:49:50Z |
|
| dc.identifier |
99e60abf-3450-4946-84e1-c71be08f41f3 |
|
| dc.identifier |
10.1080/10601325.2014.978200 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/99e60abf-3450-4946-84e1-c71be08f41f3/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/67235 |
|
| dc.description |
A series of drug-incorporating electrospun biocompatible nanofibers were fabricated by using the electrospinning process. A hydrophobic drug (ibuprofen, IBU) was directly dissolved with biopolymer systems such as polyvinyl alcohol/plasma modified chitosan (PVA/PMCh), polyvinyl alcohol/chitosan (PVA/Ch) and cellulose acetate (CA) into an organic solvent prior to electrospinning. The release of IBU from drug-loaded electrospun fibers was monitored using a quartz crystal microbalance (QCM). The results were compared with utilizing UV/Vis spectroscopy results. The biocompatible fibers were Fourier transform infrared spectroscopy (FTIR). The IBU-loaded PVA/Ch and PVA/PMCh fibers demonstrated more effective and uniform release profiles than the IBU-loaded CA fibers. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Controlled Release of Ibuprofen From Electrospun Biocompatible Nanofibers With In Situ QCM Measurements |
|
| dc.type |
info:eu-repo/semantics/article |
|