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Molecular role of catalase on oxidative stress-induced Ca2+ signaling and TRP cation channel activation in nervous system

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dc.creator NAZIROĞLU, Mustafa
dc.date 2012-05-31T21:00:00Z
dc.date.accessioned 2020-10-06T10:50:01Z
dc.date.available 2020-10-06T10:50:01Z
dc.identifier 9b387096-5f09-43a1-859a-c1049870ec55
dc.identifier 10.3109/10799893.2012.672994
dc.identifier https://avesis.sdu.edu.tr/publication/details/9b387096-5f09-43a1-859a-c1049870ec55/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/67369
dc.description Background: Catalase catalyzes the reduction of H2O2 to water and it can also remove organic hydroperoxides. Nervous system in body is especially sensitive to free radical damage due to rich content of easily oxidizible fatty acids and relatively low content of antioxidants including catalase. Recent studies indicate that reactive oxygen species actually target active channel function, in particular TRP channels. I review the effects of catalase on Ca2+ signaling and on TRP channel activation in neuroglial cells such as microglia and substantia nigra.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Molecular role of catalase on oxidative stress-induced Ca2+ signaling and TRP cation channel activation in nervous system
dc.type info:eu-repo/semantics/article


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