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Effects of Bisphosphonate on Oxidative Stress Levels in Patients With Different Types of Cancer

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dc.creator KOÇER, Gülperi
dc.creator Soenmez, Tolga Taha
dc.creator Kocer, Murat
dc.creator NAZIROĞLU, Mustafa
dc.date 2014-01-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:51:34Z
dc.date.available 2020-10-06T10:51:34Z
dc.identifier a73cfc1a-eae3-4e56-97c1-174c292400b0
dc.identifier 10.3109/07357907.2013.861475
dc.identifier https://avesis.sdu.edu.tr/publication/details/a73cfc1a-eae3-4e56-97c1-174c292400b0/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/68535
dc.description We investigated the effects of bisphosphonate (BP) on oxidative stress levels in blood of patients with cancer. In total, 19 patients with cancer and 21 healthy subjects were included in the study. BP was intravenously administrated to the participants for 6 weeks. The patients had higher lipid peroxidation (LP) levels in the plasma and erythrocyte samples but lower glutathione peroxidase (GSH-Px) and plasma vitamin E values. In patients treated with BP, calcium and LP levels decreased, but GSH-Px and vitamin E values improved. In conclusion, we observed that treatment with BP alleviated oxidative stress induced by cancer.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Effects of Bisphosphonate on Oxidative Stress Levels in Patients With Different Types of Cancer
dc.type info:eu-repo/semantics/article


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