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Multicenter Epidemiologic Study on Hepatocellular Carcinoma in Turkey

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dc.creator KAÇAN, TURGUT
dc.creator ALACACIOĞLU, AHMET
dc.creator Turan, Nedim
dc.creator Olmez, Sehmus
dc.creator Besiroglu, Mehmet
dc.creator Orakci, Zuat
dc.creator Dulger, Ahmet Cumhur
dc.creator Ozbay, Mehmet Fatih
dc.creator Kocer, Murat
dc.creator Bal, Oznur
dc.creator Dogan, Erkan
dc.creator ÜYETÜRK, ÜMMÜGÜL
dc.creator Kivrak, Derya
dc.creator Can, Alper
dc.creator Bayoglu, Ibrahim Vedat
dc.creator Tatli, Ali Murat
dc.date 2013-12-31T22:00:00Z
dc.date.accessioned 2020-10-06T10:59:54Z
dc.date.available 2020-10-06T10:59:54Z
dc.identifier aa3a49ff-b1fb-4834-a088-5ceff44c088d
dc.identifier 10.7314/apjcp.2014.15.6.2923
dc.identifier https://avesis.sdu.edu.tr/publication/details/aa3a49ff-b1fb-4834-a088-5ceff44c088d/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/68845
dc.description Background: Hepatocellular cancer (HCC) is one of the important health problems in Turkey, being very common and highly lethal. The aim of this study was to determine clinical, demographic features and risk factors. Materials and Methods: Nine hundred and sixth-three patients with HCC from 13 cities in Turkey were included in this study. Results: Only 205 (21%) of the 963 patients were women, with a male: female predominance of 4.8:1 and a median age of 61 years. The etiologic risk factors for HCC were hepatitis B in 555 patients (57.6%), 453 (81%) in men, and 102 (19%) in women, again with male predominance, hepatitis C in 159 (16.5%), (14.9% and 22.4%, with a higher incidence in women), and chronic alcohol abuse (more than ten years) in 137 (14.2%) (16.8% and 4.9%, higher in males). The Child-Pugh score paralleled with advanced disease stage amd also a high level of AFP. Conclusions: According to our findings the viral etiology (hepatitis B and hepatitis C infections) in the Turkish population was the most important factor in HCC development, with alcohol abuse as the third risk factor. The Child-Pugh classification and AFP levels were determined to be important prognostic factors in HCC patients.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Multicenter Epidemiologic Study on Hepatocellular Carcinoma in Turkey
dc.type info:eu-repo/semantics/article


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