| dc.creator |
Kahya, Mehmet Cemal |
|
| dc.creator |
TÖK, Levent |
|
| dc.creator |
NAZIROĞLU, Mustafa |
|
| dc.creator |
DOĞAN, Salih |
|
| dc.creator |
TÖK, Özlem |
|
| dc.date |
2013-12-31T22:00:00Z |
|
| dc.date.accessioned |
2020-10-06T11:00:09Z |
|
| dc.date.available |
2020-10-06T11:00:09Z |
|
| dc.identifier |
abdfe6c5-9fa6-45cc-a242-cf419582bff8 |
|
| dc.identifier |
10.4103/0301-4738.126166 |
|
| dc.identifier |
https://avesis.sdu.edu.tr/publication/details/abdfe6c5-9fa6-45cc-a242-cf419582bff8/oai |
|
| dc.identifier.uri |
http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/69031 |
|
| dc.description |
Introduction: Melatonin has been considered a potent antioxidant that detoxifies a variety of reactive oxygen species in many pathophysiological states of eye. The present study was designed to determine the effects of Wi-Fi exposure on the lens oxidant, antioxidant redox systems, as well as the possible protective effects of melatonin on the lens injury induced by electromagnetic radiation (EMR). Materials and Methods: Thirty-two rats were used in the current study and they were randomly divided into four equal groups as follows: First and second groups were cage-control and sham-control rats. Rats in third group were exposed to Wi-Fi (2.45 GHz) for duration of 60 min/day for 30 days. As in the third group, the fourth group was treated with melatonin. The one-hour exposure to irradiation in second, third and fourth took place at noon each day. Results: Lipid peroxidation levels in the lens were slightly higher in third (Wi-Fi) group than in cage and sham control groups although their concentrations were significantly (P < 0.05) decreased by melatonin supplementation. Glutathione peroxidase (GSH-Px) activity was significantly (P < 0.05) lower in Wi-Fi group than in cage and sham control groups although GSH-Px (P < 0.01) and reduced glutathione (P < 0.05) values were significantly higher in Wi-Fi + melatonin group than in Wi-Fi group. Conclusions: There are poor oxidative toxic effects of one hour of Wi-Fi exposure on the lens in the animals. However, melatonin supplementation in the lens seems to have protective effects on the oxidant system by modulation of GSH-Px activity. |
|
| dc.language |
eng |
|
| dc.rights |
info:eu-repo/semantics/closedAccess |
|
| dc.title |
Effects of melatonin on Wi-Fi-induced oxidative stress in lens of rats |
|
| dc.type |
info:eu-repo/semantics/article |
|