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Serum Levels of IL-4, IL-10, IL-12, IL-13 and IFN-gamma in Behçet's disease.

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dc.creator Kaya, S
dc.creator Aridogan, BC
dc.creator Inaloz, HS
dc.creator Yildirim, Mehmet
dc.creator Baz, K
dc.creator Baysal, V
dc.date 2003-07-31T21:00:00Z
dc.date.accessioned 2020-10-06T11:01:13Z
dc.date.available 2020-10-06T11:01:13Z
dc.identifier b40bf2b8-6203-4932-972d-ed54ebfe1269
dc.identifier 10.1111/j.1346-8138.2003.tb00442.x
dc.identifier https://avesis.sdu.edu.tr/publication/details/b40bf2b8-6203-4932-972d-ed54ebfe1269/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/69828
dc.description Behcet's disease (BD) is an inflammatory disease of unknown etiology. Although its pathogenesis is not fully understood, recent studies have suggested that immunological abnormalities and neutrophil hyperfunction may be involved in its etiology and pathophysiology. The immune system in BD can be characterized as a divergent cytokine production profile of the mixed Th1/Th2 cell type. In this study, we investigated the levels of interleukin (IL)-4, IL-10, IL-12, IL-13 and interferon-gamma in the sera of patients with BD, III comparison with recurrent aphthous stomatitis and healthy controls, to determine the Th1/Th2 profile of the disease. The levels of IL-4, IL-10 and IL-13 were found to be high in active BD patients, and IL-12 and interferon-gamma levels were lower In active BD patients than in inactive BD, recurrent aphthous stomatitis, and control patients.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title Serum Levels of IL-4, IL-10, IL-12, IL-13 and IFN-gamma in Behçet's disease.
dc.type info:eu-repo/semantics/article


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