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SPECTROMETRIC DETERMINATION OF LEVOFLOXACIN AND NORFLOXACIN IN TABLETS BY MULTIVARIATE CALIBRATION APPROACH

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dc.creator GOKSU, Sermin
dc.creator AKTAŞ, Ahmet Hakan
dc.date 2009-12-31T22:00:00Z
dc.date.accessioned 2020-10-06T11:01:16Z
dc.date.available 2020-10-06T11:01:16Z
dc.identifier b47cff09-4b52-45a2-b3f2-c79aa31299e5
dc.identifier https://avesis.sdu.edu.tr/publication/details/b47cff09-4b52-45a2-b3f2-c79aa31299e5/oai
dc.identifier.uri http://acikerisim.sdu.edu.tr/xmlui/handle/123456789/69874
dc.description Three multivariate calibration-prediction techniques, classical least squares (CLS), inverse least squares (ILS) and partial least squares (PLS) were applied to the spectrometric multicomponent analysis of the drug containing levofloxacin (LEVO) and norfloxacin (NORF) without any separation step. The selection of variables was studied. A series of synthetic solution containing different concentrations of LEVO and NORF were used to check the prediction ability of the CLS, ILS and PLS. The results obtained in this investigation strongly encourage us to apply these techniques for a routine analysis and quality control of the two drugs.
dc.language eng
dc.rights info:eu-repo/semantics/closedAccess
dc.title SPECTROMETRIC DETERMINATION OF LEVOFLOXACIN AND NORFLOXACIN IN TABLETS BY MULTIVARIATE CALIBRATION APPROACH
dc.type info:eu-repo/semantics/article


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